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30-Nov-2016 07:40

Neurons are cells that are specialized to receive, propagate, and transmit electrochemical impulses.In the human brain alone, there are over eighty billion neurons.An action potential can be divided into several sequential phases: threshold, rising phase, falling phase, undershoot phase, and recovery.Following several local graded depolarizations of the membrane potential, the threshold of excitation is reached, voltage-gated sodium channels are activated, which leads to an influx of Na ions.Neurons are diverse with respect to morphology and function.

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Ionotropic receptors are a combination of a receptor and an ion channel.Several techniques such as intracellular recording, patch-clamp, and voltage-clamp technique, pharmacology, confocal imaging, molecular biology, two photon laser scanning microscopy and Ca2 imaging have been used to study activity at the cellular level.